Exploiting the full potential of BACH1 as an anti-metastatic target in lung cancer

Metastasis, the spread and growth of tumour cells from primary tumours to distant organs, is responsible for 90% of cancer deaths, and the identification of new drugs that can reduce the spread of tumours is therefore an essential goal to increase survival for cancer patients. Lung and pancreatic cancer are two of the most lethal cancers, being often detected in a metastatic stage.

The project will build on previous research from the lab to better understand some of the mechanisms involved in metastasis and to identify and validate drugs that will stop lung and pancreatic cancer cells (and most likely other tumour types) from spreading to other organs.